ERA Technology
Patents
Application No.: 201910262085.3; PCT201910262085.3
Highlights
1. Rapid and User-Friendly Operation:
Results are delivered within 10-20 minutes from sample to completion, with minimal user input.
2. Ultra-High Sensitivity:
Achieves detection limits as low as 1-10 copies of target nucleic acid.
3. Robust Inhibition Resistance:
Samples require minimal preparation and can be directly used in reactions, resisting common inhibitors.
4. Isothermal Amplification:
Operates at a constant temperature between 37°C and 45°C,
reducing reliance on specialized equipment and enabling broad compatibility with basic thermal cyclers.
| Method | Traditional PCR | q-PCR | LAMP | ERA |
| Reaction Temp. | 95~55℃ | 95~55℃ | 65℃ | 37~45℃ |
| Reaction Time | 4 hours | 2 hours | 45~60 minutes | 10~20 minutes |
| Sensitivity | Moderate | High | High | High |
| Operation | Complex | Complex | Simple | Simple |
| Accuracy | Easily polluted by aerosol | High | Frequently false positives | High |
| Cost | Moderate cost | Exorbitant cost | High cost | Reasonable cost |