ERA technology
Enzymatic Recombinase Amplification (ERA ) Technology is a global leading and independent
intellectual property isothermal nucleic acid amplification technology developed by R&D team of
Suzhou GenDx. ERA uses advanced Molecular Design, Directed Evolution, Affinity Mathematics
and other technical means in the field of antibody pharmacy to transform and mutate specific
enzymes from bacteria, viruses and bacteriophages. Following that, screening of functional
mutants and optimizing of the combinations are conducted. The core recombination isothermal
amplification system was obtained. The method was applied for Chinese patents and international
patents (Application No.: 201910262085.3; PCT201910262085.3). The method can specifically
amplify trace target DNA fragments at low temperature (25-42℃). At the optimal temperature of
35-42℃, the amplification process only takes 5-20 minutes. Its low temperature adaptability and
sensitivity have made significant breakthroughs and reached the international advanced level.
Comparison of techniques
